Where to Buy Enclomiphene
Research-Grade Sourcing Guide (2026)
Enclomiphene citrate is the trans-isomer of clomiphene and is classified as a selective estrogen receptor modulator (SERM). Unlike mixed-isomer clomiphene citrate, enclomiphene is studied in isolation for its more targeted estrogen receptor antagonism at the hypothalamic-pituitary level — making it a cleaner research tool for HPG axis studies.
At a Glance
Helixera Labs Enclomiphene — $49.30
Capsule format · Third-party tested · Same or next business day · For research use only
1. Enclomiphene vs. clomiphene — a critical distinction
Clomiphene citrate (Clomid) is a 50/50 mixture of two geometric isomers: enclomiphene (trans) and zuclomiphene (cis). The two isomers have different pharmacological profiles and biological persistence.
| Property | Enclomiphene (trans) | Zuclomiphene (cis) | Clomiphene Citrate (mixed) |
|---|---|---|---|
| ER antagonism | Primary activity — hypothalamic/pituitary | Weaker, less selective | Combined, less predictable |
| Biological half-life | ~10 hours — clears rapidly | Weeks — accumulates | Mixed — accumulation risk |
| Research utility | Clean HPG axis tool — no accumulation confound | Confounding variable in longer studies | Less suitable for mechanistic research |
| Clinical research | Phase 3 trials for secondary hypogonadism | No dedicated clinical program | Approved for ovulation induction only |
2. Regulatory and clinical status
Enclomiphene reached Phase 3 clinical trials (Androxal, Repros Therapeutics) for secondary hypogonadism but did not receive FDA approval due to regulatory path complexity rather than safety or efficacy failure. It is not currently available through US pharmacies or prescribers.
As a research compound, enclomiphene is not a scheduled controlled substance and is legal to purchase for legitimate laboratory research.
Research use only. Enclomiphene sold by Helixera Labs is for laboratory research use only. Not for human or veterinary use.
3. Vendor evaluation criteria
Enclomiphene is a small molecule (MW ~441 Da) — synthesis is well-established but isomeric purity is the key quality variable. The trans/cis ratio must be verified to confirm enclomiphene is actually enclomiphene and not mixed-isomer clomiphene repackaged.
Research-Grade Enclomiphene — Vendor Checklist
- ≥98% purity from an independent laboratory
- Isomeric purity confirmation — trans-isomer content verified (not total clomiphene purity)
- HPLC with chiral column or equivalent method capable of resolving isomers
- Batch-specific COA with matching lot number
- Clearly labeled as enclomiphene citrate (trans-isomer) — not clomiphene citrate
- Research-only compliance language
Red flags: COA shows total purity only without isomeric breakdown · Product labeled as "clomiphene" or "clomid equivalent" · Standard HPLC only — chiral resolution required · Any therapeutic claims
4. 2026 pricing overview
| Format | Quality vendor range | Budget range |
|---|---|---|
| Capsules (30-count) | $40–$80 | $25–$45 |
| Powder (1g) | $60–$90 | $30–$50 |
| Liquid solution | $40–$65 | $25–$40 |
5. Helixera Labs Enclomiphene
Enclomiphene Citrate — Capsules
Trans-Isomer · SERM · Estrogen Receptor Antagonist · For research use only
- Enclomiphene citrate — trans-isomer, not mixed clomiphene
- Third-party purity tested
- Capsule format for precise research quantity control
- Same or next business day fulfillment from Ukiah, CA
- Free 2-day shipping on orders $150+
- Support: 1-866-463-0683
For research context, see the Enclomiphene Research Overview.
FAQ
Order Enclomiphene from Helixera Labs
Trans-isomer verified · Third-party tested · Same or next business day · For research use only